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HUMMR, a hypoxia- and HIF-1α–inducible protein, alters mitochondrial distribution and transport

Mitochondrial transport is critical for maintenance of normal neuronal function. Here, we identify a novel mitochondria protein, hypoxia up-regulated mitochondrial movement regulator (HUMMR), which is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 α (HIF-1α). Interestingl...

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Detalles Bibliográficos
Autores principales: Li, Yan, Lim, Seung, Hoffman, David, Aspenstrom, Pontus, Federoff, Howard J., Rempe, David A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711615/
https://www.ncbi.nlm.nih.gov/pubmed/19528298
http://dx.doi.org/10.1083/jcb.200811033