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Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice
BACKGROUND: Neuronal nitric oxide synthase (nNOS) is involved in the regulation of a diverse population of intracellular messenger systems in the brain. In humans, abnormal NOS/nitric oxide metabolism is suggested to contribute to the pathogenesis and pathophysiology of some neuropsychiatric disorde...
Autores principales: | Tanda, Koichi, Nishi, Akinori, Matsuo, Naoki, Nakanishi, Kazuo, Yamasaki, Nobuyuki, Sugimoto, Tohru, Toyama, Keiko, Takao, Keizo, Miyakawa, Tsuyoshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711944/ https://www.ncbi.nlm.nih.gov/pubmed/19538708 http://dx.doi.org/10.1186/1756-6606-2-19 |
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