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EPHA2 Is Associated with Age-Related Cortical Cataract in Mice and Humans

Age-related cataract is a major cause of blindness worldwide, and cortical cataract is the second most prevalent type of age-related cataract. Although a significant fraction of age-related cataract is heritable, the genetic basis remains to be elucidated. We report that homozygous deletion of Epha2...

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Detalles Bibliográficos
Autores principales: Jun, Gyungah, Guo, Hong, Klein, Barbara E. K., Klein, Ronald, Wang, Jie Jin, Mitchell, Paul, Miao, Hui, Lee, Kristine E., Joshi, Tripti, Buck, Matthias, Chugha, Preeti, Bardenstein, David, Klein, Alison P., Bailey-Wilson, Joan E., Gong, Xiaohua, Spector, Tim D., Andrew, Toby, Hammond, Christopher J., Elston, Robert C., Iyengar, Sudha K., Wang, Bingcheng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712078/
https://www.ncbi.nlm.nih.gov/pubmed/19649315
http://dx.doi.org/10.1371/journal.pgen.1000584