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CCR3 is a therapeutic and diagnostic target for neovascular age-related macular degeneration
Age-related macular degeneration (AMD), a leading cause of blindness worldwide, is as prevalent as cancer in industrialized nations. Most blindness in AMD results from invasion of the retina by choroidal neovascularization (CNV). We report that the eosinophil/mast cell chemokine receptor CCR3 is spe...
Autores principales: | Takeda, Atsunobu, Baffi, Judit Z., Kleinman, Mark E., Cho, Won Gil, Nozaki, Miho, Yamada, Kiyoshi, Kaneko, Hiroki, Albuquerque, Romulo J.C., Dridi, Sami, Saito, Kuniharu, Raisler, Brian J., Budd, Steven J., Geisen, Pete, Munitz, Ariel, Ambati, Balamurali K., Green, Martha G., Ishibashi, Tatsuro, Wright, John D., Humbles, Alison A., Gerard, Craig J., Ogura, Yuichiro, Pan, Yuzhen, Smith, Justine R., Grisanti, Salvatore, Hartnett, M. Elizabeth, Rothenberg, Marc E., Ambati, Jayakrishna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712122/ https://www.ncbi.nlm.nih.gov/pubmed/19525930 http://dx.doi.org/10.1038/nature08151 |
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