T-bet controls regulatory T cell homeostasis and function during type-1 inflammation

Several subsets of Foxp3(+) regulatory T (T(reg)) cells work in concert to maintain immune homeostasis. However, the molecular bases underlying the phenotypic and functional diversity of T(reg) cells remain obscure. We show that in response to interferon-γ, Foxp3(+) T(reg) cells upregulated the T he...

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Detalles Bibliográficos
Autores principales: Koch, Meghan A., Tucker-Heard, Glady’s, Perdue, Nikole R., Killebrew, Justin R., Urdahl, Kevin B., Campbell, Daniel J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712126/
https://www.ncbi.nlm.nih.gov/pubmed/19412181
http://dx.doi.org/10.1038/ni.1731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712126/
https://www.ncbi.nlm.nih.gov/pubmed/19412181
http://dx.doi.org/10.1038/ni.1731

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