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T-bet controls regulatory T cell homeostasis and function during type-1 inflammation
Several subsets of Foxp3(+) regulatory T (T(reg)) cells work in concert to maintain immune homeostasis. However, the molecular bases underlying the phenotypic and functional diversity of T(reg) cells remain obscure. We show that in response to interferon-γ, Foxp3(+) T(reg) cells upregulated the T he...
Autores principales: | Koch, Meghan A., Tucker-Heard, Glady’s, Perdue, Nikole R., Killebrew, Justin R., Urdahl, Kevin B., Campbell, Daniel J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712126/ https://www.ncbi.nlm.nih.gov/pubmed/19412181 http://dx.doi.org/10.1038/ni.1731 |
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