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Detection and Trapping of Intermediate States Priming Nicotinic Receptor Channel Opening
In the course of synaptic transmission in the brain and periphery, acetylcholine receptors (AChRs) rapidly transduce a chemical signal into an electrical impulse. The speed of transduction owes in large part to rapid ACh association and dissociation, implying a binding site relatively non-selective...
Autores principales: | Mukhtasimova, Nuriya, Lee, Won Yong, Wang, Hai-Long, Sine, Steven M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712348/ https://www.ncbi.nlm.nih.gov/pubmed/19339970 http://dx.doi.org/10.1038/nature07923 |
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