Numb regulates cell–cell adhesion and polarity in response to tyrosine kinase signalling

Epithelial-mesenchymal transition (EMT), which can be caused by aberrant tyrosine kinase signalling, marks epithelial tumour progression and metastasis, yet the underlying molecular mechanism is not fully understood. Here, we report that Numb interacts with E-cadherin (E-cad) through its phosphotyro...

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Detalles Bibliográficos
Autores principales: Wang, Zezhou, Sandiford, Shelley, Wu, Chenggang, Li, Shawn Shun-Cheng
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712596/
https://www.ncbi.nlm.nih.gov/pubmed/19609305
http://dx.doi.org/10.1038/emboj.2009.190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712596/
https://www.ncbi.nlm.nih.gov/pubmed/19609305
http://dx.doi.org/10.1038/emboj.2009.190

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