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Interpreting a Low Resolution Map of Human U1 snRNP Using Anomalous Scatterers

We recently determined the crystal structure of the functional core of human U1 snRNP, consisting of nine proteins and one RNA, based on a 5.5 Å resolution electron density map. At 5–7 Å resolution, α helices and β sheets appear as rods and slabs, respectively, hence it is not possible to determine...

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Detalles Bibliográficos
Autores principales: Oubridge, Chris, Krummel, Daniel A. Pomeranz, Leung, Adelaine K.-W., Li, Jade, Nagai, Kiyoshi
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712673/
https://www.ncbi.nlm.nih.gov/pubmed/19604473
http://dx.doi.org/10.1016/j.str.2009.05.009