Cargando…

Systematic Analysis of Immune Infiltrates in High-Grade Serous Ovarian Cancer Reveals CD20, FoxP3 and TIA-1 as Positive Prognostic Factors

BACKGROUND: Tumor-infiltrating T cells are associated with survival in epithelial ovarian cancer (EOC), but their functional status is poorly understood, especially relative to the different risk categories and histological subtypes of EOC. METHODOLOGY/PRINCIPAL FINDINGS: Tissue microarrays containi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milne, Katy, Köbel, Martin, Kalloger, Steven E., Barnes, Rebecca O., Gao, Dongxia, Gilks, C. Blake, Watson, Peter H., Nelson, Brad H.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712762/ https://www.ncbi.nlm.nih.gov/pubmed/19641607 http://dx.doi.org/10.1371/journal.pone.0006412

Ejemplares similares

Correction: Systematic Analysis of Immune Infiltrates in High-Grade Serous Ovarian Cancer Reveals CD20, FoxP3 and TIA-1 as Positive Prognostic Factors
por: Milne, Katy, et al.
Publicado: (2013)

Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes
por: Milne, Katy, et al.
Publicado: (2012)

Tumor-Infiltrating T Cells Correlate with NY-ESO-1-Specific Autoantibodies in Ovarian Cancer
por: Milne, Katy, et al.
Publicado: (2008)

Molecular Abnormalities in Ovarian Cancer Subtypes Other than High-Grade Serous Carcinoma
por: Gilks, C. Blake
Publicado: (2010)

Markers of T Cell Infiltration and Function Associate with Favorable Outcome in Vascularized High-Grade Serous Ovarian Carcinoma
por: Townsend, Katelin N., et al.
Publicado: (2013)

Low grade serous carcinoma of the peritoneum in a BRCA1 carrier previously diagnosed with a “low-grade serous tubal intra-epithelial carcinoma” (STIC) on risk reducing surgery
por: Chay, Wen Yee, et al.
Publicado: (2015)

Prognostic Value of Tumor-Infiltrating FoxP3(+) T Cells in Gastrointestinal Cancers: A Meta Analysis
por: Huang, Yong, et al.
Publicado: (2014)

Spatial distribution of FoxP3+ and CD8+ tumour infiltrating T cells reflects their functional activity
por: Posselt, Rebecca, et al.
Publicado: (2016)

Tumor‐infiltrating FoxP3+ T cells are associated with poor prognosis in oral squamous cell carcinoma
por: Hayashi, Tomio, et al.
Publicado: (2021)

DNA facilitates heterodimerization between human transcription factors FoxP1 and FoxP2 by increasing their conformational flexibility
por: Coñuecar, Ricardo, et al.
Publicado: (2023)

FoxP3- and CD8-positive Infiltrating Immune Cells Together Determine Clinical Outcome in Colorectal Cancer
por: Zeestraten, Eliane C. M., et al.
Publicado: (2011)

Regulatory T Cells in Pregnancy: It Is Not All About FoxP3
por: Krop, Juliette, et al.
Publicado: (2020)

Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma
por: Tessier-Cloutier, Basile, et al.
Publicado: (2017)

Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
por: West, Nathan R, et al.
Publicado: (2011)

Accelerated FoxP2 Evolution in Echolocating Bats
por: Li, Gang, et al.
Publicado: (2007)

FoxP3 gets a new gig
por: Van Epps, Heather L.
Publicado: (2005)

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
por: Bashashati, Ali, et al.
Publicado: (2013)

Prognostic value of tumor-infiltrating FoxP3(+) regulatory T cells in cancers: a systematic review and meta-analysis
por: Shang, Bin, et al.
Publicado: (2015)

Tumor-infiltrating FoxP3(+) Tregs predict favorable outcome in colorectal cancer patients: A meta-analysis
por: Hu, Guoming, et al.
Publicado: (2017)

Spatial Distribution and Prognostic Implications of Tumor-Infiltrating FoxP3(−) CD4(+) T Cells in Biliary Tract Cancer
por: Kim, Hyung-Don, et al.
Publicado: (2021)

Gross genomic alterations and gene expression profiles of high- grade serous carcinoma of the ovary with and without BRCA1 inactivation
por: Pradhan, Manohar, et al.
Publicado: (2010)

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas
por: Tone, Alicia A, et al.
Publicado: (2014)

Mapping the distribution of language related genes FoxP1, FoxP2, and CntnaP2 in the brains of vocal learning bat species
por: Rodenas‐Cuadrado, Pedro M., et al.
Publicado: (2018)

Regulation of FoxP3(+) Regulatory T Cells and Th17 Cells by Retinoids
por: Kim, Chang H.
Publicado: (2008)

Location, location, location: CD103 demarcates intraepithelial, prognostically favorable CD8(+) tumor-infiltrating lymphocytes in ovarian cancer
por: Webb, John R, et al.
Publicado: (2014)

Drosophila FoxP Mutants Are Deficient in Operant Self-Learning
por: Mendoza, Ezequiel, et al.
Publicado: (2014)

Conserved regulation of neurodevelopmental processes and behavior by FoxP in Drosophila
por: Castells-Nobau, Anna, et al.
Publicado: (2019)

Infiltration of FoxP3+ Regulatory T Cells is a Strong and Independent Prognostic Factor in Head and Neck Squamous Cell Carcinoma
por: Seminerio, Imelda, et al.
Publicado: (2019)

CXCL12 is associated with FoxP3(+) tumor-infiltrating lymphocytes and affects the survival of patients with oral squamous cell carcinoma
por: Zhang, Bowen, et al.
Publicado: (2019)

Expression of PD-L1 in cervical carcinoma and its impact on survival associated with T-cell infiltration and FoxP3 expression
por: Grochot, Rafael M, et al.
Publicado: (2019)

The prognostic value of intratumoral and peritumoral tumor-infiltrating FoxP3+Treg cells in of pancreatic adenocarcinoma: a meta-analysis
por: Hu, Lingyu, et al.
Publicado: (2021)

The correlation between infiltration of FoxP3(+) Tregs, CD66b(+) TANs and CD163(+) TAMs in colorectal cancer
por: Ren, Yuehan, et al.
Publicado: (2022)

MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary
por: Lee, Cheng-Han, et al.
Publicado: (2009)

Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
por: West, N R, et al.
Publicado: (2013)

Unraveling the identity of FoxP3+ regulatory T cells in Granulomatosis with Polyangiitis patients
por: Reijnders, Tom D. Y., et al.
Publicado: (2019)

Molecular characterization of low-grade serous ovarian carcinoma identifies genomic aberrations according to hormone receptor expression
por: Cheasley, Dane, et al.
Publicado: (2022)

Long non-coding RNA FOXP4-AS1 is a prognostic biomarker and associated with immune infiltrates in ovarian serous cystadenocarcinoma
por: Liao, Cheng, et al.
Publicado: (2021)

Increased CD3(+), CD8(+), or FoxP3(+) T Lymphocyte Infiltrations Are Associated with the Pathogenesis of Colorectal Cancer but Not with the Overall Survival of Patients
por: Barbosa, Ana Margarida, et al.
Publicado: (2021)

Alternative Splicing and Gene Duplication in the Evolution of the FoxP Gene Subfamily
por: Santos, M. Emília, et al.
Publicado: (2011)

FoxP3(+) Regulatory T Cells Attenuate Experimental Necrotizing Enterocolitis
por: Dingle, Bridgette M., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_123ica3tq96qbvklav3n71u3jo