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A Functional Melanocortin System May Be Required for Chronic CNS-Mediated Antidiabetic and Cardiovascular Actions of Leptin
OBJECTIVE: We recently showed that leptin has powerful central nervous system (CNS)-mediated antidiabetic and cardiovascular actions. This study tested whether the CNS melanocortin system mediates these actions of leptin in diabetic rats. RESEARCH DESIGN AND METHODS: A cannula was placed in the late...
Autores principales: | da Silva, Alexandre A., do Carmo, Jussara M., Freeman, J. Nathan, Tallam, Lakshmi S., Hall, John E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712780/ https://www.ncbi.nlm.nih.gov/pubmed/19491210 http://dx.doi.org/10.2337/db08-1221 |
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