Genetic Disruption of Myostatin Reduces the Development of Proatherogenic Dyslipidemia and Atherogenic Lesions In Ldlr Null Mice

OBJECTIVE: Insulin-resistant states, such as obesity and type 2 diabetes, contribute substantially to accelerated atherogenesis. Null mutations of myostatin (Mstn) are associated with increased muscle mass and decreased fat mass. In this study, we determined whether Mstn disruption could prevent the...

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Detalles Bibliográficos
Autores principales: Tu, Powen, Bhasin, Shalender, Hruz, Paul W., Herbst, Karen L., Castellani, Lawrence W., Hua, Ning, Hamilton, James A., Guo, Wen
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712781/
https://www.ncbi.nlm.nih.gov/pubmed/19509018
http://dx.doi.org/10.2337/db09-0349

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