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Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet–Induced Obese Mice Lacking Malonyl CoA Decarboxylase
OBJECTIVE: Whereas an impaired ability to oxidize fatty acids is thought to contribute to intracellular lipid accumulation, insulin resistance, and cardiac dysfunction, high rates of fatty acid oxidation could also impair glucose metabolism and function. We therefore determined the effects of diet-i...
Autores principales: | Ussher, John R., Koves, Timothy R., Jaswal, Jagdip S., Zhang, Liyan, Ilkayeva, Olga, Dyck, Jason R.B., Muoio, Deborah M., Lopaschuk, Gary D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712785/ https://www.ncbi.nlm.nih.gov/pubmed/19478144 http://dx.doi.org/10.2337/db09-0011 |
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