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Endoplasmic Reticulum Stress Regulates Adipocyte Resistin Expression

OBJECTIVE: Resistin is a secreted polypeptide that impairs glucose metabolism and, in rodents, is derived exclusively from adipocytes. In murine obesity, resistin circulates at elevated levels but its gene expression in adipose tissue is paradoxically reduced. The mechanism behind the downregulation...

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Detalles Bibliográficos
Autores principales: Lefterova, Martina I., Mullican, Shannon E., Tomaru, Takuya, Qatanani, Mohammed, Schupp, Michael, Lazar, Mitchell A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712799/
https://www.ncbi.nlm.nih.gov/pubmed/19491212
http://dx.doi.org/10.2337/db08-1706

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