Demonstration of catch bonds between an integrin and its ligand

Binding of integrins to ligands provides anchorage and signals for the cell, making them prime candidates for mechanosensing molecules. How force regulates integrin–ligand dissociation is unclear. We used atomic force microscopy to measure the force-dependent lifetimes of single bonds between a fibr...

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Detalles Bibliográficos
Autores principales: Kong, Fang, García, Andrés J., Mould, A. Paul, Humphries, Martin J., Zhu, Cheng
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712956/
https://www.ncbi.nlm.nih.gov/pubmed/19564406
http://dx.doi.org/10.1083/jcb.200810002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712956/
https://www.ncbi.nlm.nih.gov/pubmed/19564406
http://dx.doi.org/10.1083/jcb.200810002

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