Motor-dependent microtubule disassembly driven by tubulin tyrosination

In cells, stable microtubules (MTs) are covalently modified by a carboxypeptidase, which removes the C-terminal Tyr residue of α-tubulin. The significance of this selective detyrosination of MTs is not understood. In this study, we report that tubulin detyrosination in fibroblasts inhibits MT disass...

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Detalles Bibliográficos
Autores principales: Peris, Leticia, Wagenbach, Michael, Lafanechère, Laurence, Brocard, Jacques, Moore, Ayana T., Kozielski, Frank, Job, Didier, Wordeman, Linda, Andrieux, Annie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712961/
https://www.ncbi.nlm.nih.gov/pubmed/19564401
http://dx.doi.org/10.1083/jcb.200902142

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