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The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy
Hypusination is a unique posttranslational modification by which lysine is transformed into the atypical amino acid hypusine. eIF5A (eukaryotic initiation factor 5A) is the only known protein to contain hypusine. In this study, we describe the identification and characterization of nero, the Drosoph...
Autores principales: | Patel, Prajal H., Costa-Mattioli, Mauro, Schulze, Karen L., Bellen, Hugo J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712966/ https://www.ncbi.nlm.nih.gov/pubmed/19546244 http://dx.doi.org/10.1083/jcb.200904161 |
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