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A structural model for K(2P) potassium channels based on 23 pairs of interacting sites and continuum electrostatics

K(2P)Ø, the two-pore domain potassium background channel that determines cardiac rhythm in Drosophila melanogaster, and its homologues that establish excitable membrane activity in mammals are of unknown structure. K(2P) subunits have two pore domains flanked by transmembrane (TM) spans: TM1-P1-TM2-...

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Detalles Bibliográficos
Autores principales:	Kollewe, Astrid, Lau, Albert Y., Sullivan, Ashley, Benoît Roux, Goldstein, Steve A.N.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712977/ https://www.ncbi.nlm.nih.gov/pubmed/19564427 http://dx.doi.org/10.1085/jgp.200910235

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