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Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel
N-type inactivation of voltage-gated potassium channels is an autoinhibitory process that occurs when the N terminus binds within the channel pore and blocks conduction. N-type inactivation and recovery occur with single-exponential kinetics, consistent with a single-step reaction where binding and...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712980/ https://www.ncbi.nlm.nih.gov/pubmed/19528261 http://dx.doi.org/10.1085/jgp.200910219 |