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Ca(2+) signaling evoked by activation of Na(+) channels and Na(+)/Ca(2+) exchangers is required for GABA-induced NG2 cell migration

NG2 cells originate from various brain regions and migrate to their destinations during early development. These cells express voltage-gated Na(+) channels but fail to produce typical action potentials. The physiological role of Na(+) channels in these cells is unclear. We found that GABA induces me...

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Detalles Bibliográficos
Autores principales: Tong, Xiao-ping, Li, Xiang-yao, Zhou, Bing, Shen, Wanhua, Zhang, Zhi-jun, Xu, Tian-le, Duan, Shumin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712990/
https://www.ncbi.nlm.nih.gov/pubmed/19596850
http://dx.doi.org/10.1083/jcb.200811071