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The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction

Cadherin-based adherens junctions (AJs) mediate cell adhesion and regulate cell shape change. The nectin–afadin complex also localizes to AJs and links to the cytoskeleton. Mammalian afadin has been suggested to be essential for adhesion and polarity establishment, but its mechanism of action is unc...

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Detalles Bibliográficos
Autores principales: Sawyer, Jessica K., Harris, Nathan J., Slep, Kevin C., Gaul, Ulrike, Peifer, Mark
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712996/
https://www.ncbi.nlm.nih.gov/pubmed/19596848
http://dx.doi.org/10.1083/jcb.200904001