IL-7 signaling in dendritic cells regulates CD4(+) T cell homeostatic proliferation and CD4(+) T cell niche size

Interleukin 7 (IL-7) and T cell receptor (TCR) signals have been proposed to be the primary drivers of homeostatic T cell proliferation. However, it is not known why CD4(+) T cells undergo less efficient homeostatic proliferation than CD8(+) T cells. Here we showed that systemic IL-7 concentrations...

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Detalles Bibliográficos
Autores principales: Guimond, Martin, Veenstra, Rachelle G., Grindler, David J., Zhang, Hua, Cui, Yongzhi, Murphy, Ryan D., Kim, Su Young, Na, Risu, Henninghausen, Lothar, Kurtulus, Sema, Erman, Batu, Matzinger, Polly, Merchant, Melinda S., Mackall1, Crystal L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713006/
https://www.ncbi.nlm.nih.gov/pubmed/19136960
http://dx.doi.org/10.1038/ni.1695

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