A novel hirudin derivative characterized with anti-platelet aggregations and thrombin inhibition

Background Hirudin is an anti-coagulative product of the salivary glands of the medicinal leech Hirudo medicinalis. It is a powerful and specific thrombin inhibitor. Peptides containing the RGD motif competitively inhibit the binding of fibrinogen to GP IIb/IIIa on the platelets, thus inhibiting pla...

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Detalles Bibliográficos
Autores principales: Mo, Wei, Zhang, Yan-Ling, Chen, Hong-Shan, Wang, Long-Sheng, Song, Hou-Yan
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713024/
https://www.ncbi.nlm.nih.gov/pubmed/18998199
http://dx.doi.org/10.1007/s11239-008-0251-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713024/
https://www.ncbi.nlm.nih.gov/pubmed/18998199
http://dx.doi.org/10.1007/s11239-008-0251-9

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