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Conformational changes in a pore-forming region underlie voltage-dependent “loop gating” of an unapposed connexin hemichannel
The structure of the pore is critical to understanding the molecular mechanisms underlying selective permeation and voltage-dependent gating of channels formed by the connexin gene family. Here, we describe a portion of the pore structure of unapposed hemichannels formed by a Cx32 chimera, Cx32*Cx43...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713147/ https://www.ncbi.nlm.nih.gov/pubmed/19468074 http://dx.doi.org/10.1085/jgp.200910207 |