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Manipulation of Signaling Thresholds in “Engineered Stem Cell Niches” Identifies Design Criteria for Pluripotent Stem Cell Screens

In vivo, stem cell fate is regulated by local microenvironmental parameters. Governing parameters in this stem cell niche include soluble factors, extra-cellular matrix, and cell-cell interactions. The complexity of this in vivo niche limits analyses into how individual niche parameters regulate ste...

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Detalles Bibliográficos
Autores principales:	Peerani, Raheem, Onishi, Kento, Mahdavi, Alborz, Kumacheva, Eugenia, Zandstra, Peter W.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713412/ https://www.ncbi.nlm.nih.gov/pubmed/19649273 http://dx.doi.org/10.1371/journal.pone.0006438

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