Constitutional Flavonoids Derived from Epimedium Dose-Dependently Reduce Incidence of Steroid-Associated Osteonecrosis Not via Direct Action by Themselves on Potential Cellular Targets

Intravascular-thrombosis and extravascular-lipid-deposit are the two key pathogenic events considered to interrupt intraosseous blood supply during development of steroid-associated osteonecrosis (ON). However, there are no clinically employed agents capable of simultaneously targeting these two key...

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Detalles Bibliográficos
Autores principales: Zhang, Ge, Wang, Xin-Luan, Sheng, Hui, Xie, Xin-Hui, He, Yi-Xin, Yao, Xin-Sheng, Li, Zi-Rong, Lee, Kwong-Man, He, Wei, Leung, Kwok-Sui, Qin, Ling
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713419/
https://www.ncbi.nlm.nih.gov/pubmed/19641620
http://dx.doi.org/10.1371/journal.pone.0006419

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