Structure/Function Analysis of PARP-1 in Oxidative and Nitrosative Stress-Induced Monomeric ADPR Formation

Poly adenosine diphosphate-ribose polymerase-1 (PARP-1) is a multifunctional enzyme that is involved in two major cellular responses to oxidative and nitrosative (O/N) stress: detection and response to DNA damage via formation of protein-bound poly adenosine diphosphate-ribose (PAR), and formation o...

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Detalles Bibliográficos
Autores principales: Buelow, Ben, Uzunparmak, Burak, Paddock, Marcia, Scharenberg, Andrew M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713433/
https://www.ncbi.nlm.nih.gov/pubmed/19641624
http://dx.doi.org/10.1371/journal.pone.0006339

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