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Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer

RNA interference is a powerful tool for the functional analysis of proteins by specific gene knockdown. In this study, we devised a rapid and efficient way to screen suitable siRNA sequences and subsequently employ them for specific gene knockdown in usually hard-to-transfect lymphoid cell lines, us...

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Detalles Bibliográficos
Autores principales: Anastasov, Nataša, Klier, Margit, Koch, Ina, Angermeier, Daniela, Höfler, Heinz, Fend, Falko, Quintanilla-Martinez, Leticia
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713496/
https://www.ncbi.nlm.nih.gov/pubmed/19669218
http://dx.doi.org/10.1007/s12308-008-0020-x