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Expression of COX-2, NF-κB-p65, NF-κB-p50 and IKKα in malignant and adjacent normal human colorectal tissue

BACKGROUND: Cyclooxygenase-2 (COX-2) is selectively over-expressed in colorectal tumours. The mechanism of COX-2 induction in these tumours is not fully understood, although evidence suggests a possible link between nuclear factor (NF)-κB and COX-2. We hypothesised an association between COX-2 expre...

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Detalles Bibliográficos
Autores principales:	Charalambous, M P, Lightfoot, T, Speirs, V, Horgan, K, Gooderham, N J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713702/ https://www.ncbi.nlm.nih.gov/pubmed/19513071 http://dx.doi.org/10.1038/sj.bjc.6605120

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