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Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib
The proteasome inhibitor and anti-cancer drug bortezomib was tested for in vitro activity against bloodstream forms of Trypanosoma brucei. The concentrations of bortezomib required to reduce the growth rate by 50% and to kill all trypanosomes were 3.3 nM and 10 nM, respectively. In addition, bortezo...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714034/ https://www.ncbi.nlm.nih.gov/pubmed/19583840 http://dx.doi.org/10.1186/1756-3305-2-29 |