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Evolutionary Processes Acting on Candidate cis-Regulatory Regions in Humans Inferred from Patterns of Polymorphism and Divergence
Analysis of polymorphism and divergence in the non-coding portion of the human genome yields crucial information about factors driving the evolution of gene regulation. Candidate cis-regulatory regions spanning more than 15,000 genes in 15 African Americans and 20 European Americans were re-sequence...
Autores principales: | Torgerson, Dara G., Boyko, Adam R., Hernandez, Ryan D., Indap, Amit, Hu, Xiaolan, White, Thomas J., Sninsky, John J., Cargill, Michele, Adams, Mark D., Bustamante, Carlos D., Clark, Andrew G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714078/ https://www.ncbi.nlm.nih.gov/pubmed/19662163 http://dx.doi.org/10.1371/journal.pgen.1000592 |
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