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Towards a Clinically Relevant Lentiviral Transduction Protocol for Primary Human CD34(+) Hematopoietic Stem/Progenitor Cells

BACKGROUND: Hematopoietic stem cells (HSC), in particular mobilized peripheral blood stem cells, represent an attractive target for cell and gene therapy. Efficient gene delivery into these target cells without compromising self-renewal and multi-potency is crucial for the success of gene therapy. W...

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Detalles Bibliográficos
Autores principales:	Millington, Michelle, Arndt, Allison, Boyd, Maureen, Applegate, Tanya, Shen, Sylvie
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714083/ https://www.ncbi.nlm.nih.gov/pubmed/19649289 http://dx.doi.org/10.1371/journal.pone.0006461

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