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Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis

INTRODUCTION: Reconstitution of peripheral blood (PB) B cells after therapeutic depletion with the chimeric anti-CD20 antibody rituximab (RTX) mimics lymphatic ontogeny. In this situation, the repletion kinetics and migratory properties of distinct developmental B-cell stages and their correlation t...

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Detalles Bibliográficos
Autores principales: Möller, Burkhard, Aeberli, Daniel, Eggli, Stefan, Fuhrer, Martin, Vajtai, Istvan, Vögelin, Esther, Ziswiler, Hans-Rudolf, Dahinden, Clemens A, Villiger, Peter M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714106/
https://www.ncbi.nlm.nih.gov/pubmed/19419560
http://dx.doi.org/10.1186/ar2686

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