Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration

INTRODUCTION: The aim of this study was to compare the effects of tumour necrosis factor-alpha (TNF-α) and interleukin-1-beta (IL-1β) on protease and catabolic cytokine and receptor gene expression in normal and degenerate human nucleus pulposus cells in alginate culture. METHODS: Cells isolated fro...

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Detalles Bibliográficos
Autores principales: Millward-Sadler, S Jane, Costello, Patrick W, Freemont, Anthony J, Hoyland, Judith A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714110/
https://www.ncbi.nlm.nih.gov/pubmed/19435506
http://dx.doi.org/10.1186/ar2693

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