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Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

INTRODUCTION: Anti-TNF therapies have revolutionized the treatment of rheumatoid arthritis (RA), a common systemic autoimmune disease involving destruction of the synovial joints. However, in the practice of rheumatology approximately one-third of patients demonstrate no clinical improvement in resp...

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Detalles Bibliográficos
Autores principales: Hueber, Wolfgang, Tomooka, Beren H, Batliwalla, Franak, Li, Wentian, Monach, Paul A, Tibshirani, Robert J, Van Vollenhoven, Ronald F, Lampa, Jon, Saito, Kazuyoshi, Tanaka, Yoshiya, Genovese, Mark C, Klareskog, Lars, Gregersen, Peter K, Robinson, William H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714123/
https://www.ncbi.nlm.nih.gov/pubmed/19460157
http://dx.doi.org/10.1186/ar2706