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Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage
INTRODUCTION: Disorders that affect glucose metabolism, namely diabetes mellitus (DM), may favor the development and/or progression of osteoarthritis (OA). Thus far, little is known regarding the ability of chondrocytes to adjust to variations in the extracellular glucose concentration, resulting fr...
Autores principales: | Rosa, Susana C, Gonçalves, Juliana, Judas, Fernando, Mobasheri, Ali, Lopes, Celeste, Mendes, Alexandrina F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714130/ https://www.ncbi.nlm.nih.gov/pubmed/19490621 http://dx.doi.org/10.1186/ar2713 |
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