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Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis

INTRODUCTION: Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been reported to decrease susceptibility to rheumatoid a...

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Detalles Bibliográficos
Autores principales: Rossol, Manuela, Pierer, Matthias, Arnold, Sybille, Keyßer, Gernot, Burkhardt, Harald, Baerwald, Christoph, Wagner, Ulf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714147/
https://www.ncbi.nlm.nih.gov/pubmed/19538721
http://dx.doi.org/10.1186/ar2733