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How Thioredoxin Dissociates Its Mixed Disulfide

The dissociation mechanism of the thioredoxin (Trx) mixed disulfide complexes is unknown and has been debated for more than twenty years. Specifically, opposing arguments for the activation of the nucleophilic cysteine as a thiolate during the dissociation of the complex have been put forward. As a...

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Detalles Bibliográficos
Autores principales:	Roos, Goedele, Foloppe, Nicolas, Van Laer, Koen, Wyns, Lode, Nilsson, Lennart, Geerlings, Paul, Messens, Joris
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714181/ https://www.ncbi.nlm.nih.gov/pubmed/19675666 http://dx.doi.org/10.1371/journal.pcbi.1000461

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