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Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation

The study shows constitutive activation of the Notch pathway in various types of malignancies. However, it remains unclear how the Notch pathway is involved in the pathogenesis of osteosarcoma. We investigated the expression of the Notch pathway molecules in osteosarcoma biopsy specimens and examine...

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Detalles Bibliográficos
Autores principales:	Tanaka, M, Setoguchi, T, Hirotsu, M, Gao, H, Sasaki, H, Matsunoshita, Y, Komiya, S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714252/ https://www.ncbi.nlm.nih.gov/pubmed/19455146 http://dx.doi.org/10.1038/sj.bjc.6605060

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