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Punicic Acid a Conjugated Linolenic Acid Inhibits TNFα-Induced Neutrophil Hyperactivation and Protects from Experimental Colon Inflammation in Rats

BACKGROUND: Neutrophils play a major role in inflammation by releasing large amounts of ROS produced by NADPH-oxidase and myeloperoxidase (MPO). The proinflammatory cytokine TNFα primes ROS production through phosphorylation of the NADPH-oxidase subunit p47phox on Ser345. Conventional anti-inflammat...

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Detalles Bibliográficos
Autores principales:	Boussetta, Tarek, Raad, Houssam, Lettéron, Philippe, Gougerot-Pocidalo, Marie-Anne, Marie, Jean-Claude, Driss, Fathi, El-Benna, Jamel
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714468/ https://www.ncbi.nlm.nih.gov/pubmed/19649246 http://dx.doi.org/10.1371/journal.pone.0006458

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