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Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris
BACKGROUND: VAR2CSA is the main candidate for a vaccine against pregnancy-associated malaria, but vaccine development is complicated by the large size and complex disulfide bonding pattern of the protein. Recent X-ray crystallographic information suggests that domain boundaries of VAR2CSA Duffy bind...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714522/ https://www.ncbi.nlm.nih.gov/pubmed/19563628 http://dx.doi.org/10.1186/1475-2875-8-143 |