Cargando…
Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone receptor family, which is defined as transcriptional factors that are activated by the binding of ligands to their ligand-binding domains (LBDs). Although the three PPAR subtypes display different tissue distribution p...
Autores principales: | Oyama, Takuji, Toyota, Kenji, Waku, Tsuyoshi, Hirakawa, Yuko, Nagasawa, Naoko, Kasuga, Jun-ichi, Hashimoto, Yuichi, Miyachi, Hiroyuki, Morikawa, Kosuke |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714719/ https://www.ncbi.nlm.nih.gov/pubmed/19622862 http://dx.doi.org/10.1107/S0907444909015935 |
Ejemplares similares
-
Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial Agonists
por: Liberato, Marcelo Vizoná, et al.
Publicado: (2012) -
Structural Development Studies of Subtype-Selective Ligands for Peroxisome Proliferator-Activated Receptors (PPARs) Based on the 3,4-Disubstituted Phenylpropanoic Acid Scaffold as a Versatile Template
por: Miyachi, Hiroyuki, et al.
Publicado: (2008) -
The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer
por: Huang, Runzhi, et al.
Publicado: (2020) -
Structural Biology Inspired Development of a Series of Human Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Ligands: From Agonist to Antagonist
por: Miyachi, Hiroyuki
Publicado: (2023) -
Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone
por: Syversen, Unni, et al.
Publicado: (2009)