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Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers

OBJECTIVE: There is limited pharmacokinetic data available for the combination artesunate + amodiaquine, which is used widely to treat uncomplicated malaria. This study examines the bioavailability and tolerability of a fixed (200 mg artesunate + 540 mg amodiaquine) and loose (200 mg + 612 mg) combi...

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Detalles Bibliográficos
Autores principales:	Navaratnam, Visweswaran, Ramanathan, Surash, Wahab, Mohd Suhaimi Ab., Siew Hua, Gan, Mansor, Sharif Mahsufi, Kiechel, Jean-René, Vaillant, Michel, Taylor, Walter R. J., Olliaro, Piero
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Pharmacokinetics and Disposition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714898/ https://www.ncbi.nlm.nih.gov/pubmed/19404632 http://dx.doi.org/10.1007/s00228-009-0656-1

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