Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

Netherton syndrome (NS) is a severe genetic skin disease with constant atopic manifestations that is caused by mutations in the serine protease inhibitor Kazal-type 5 (SPINK5) gene, which encodes the protease inhibitor lymphoepithelial Kazal-type–related inhibitor (LEKTI). Lack of LEKTI causes strat...

Descripción completa

Detalles Bibliográficos
Autores principales: Briot, Anaïs, Deraison, Céline, Lacroix, Matthieu, Bonnart, Chrystelle, Robin, Aurélie, Besson, Céline, Dubus, Pierre, Hovnanian, Alain
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715042/
https://www.ncbi.nlm.nih.gov/pubmed/19414552
http://dx.doi.org/10.1084/jem.20082242

Ejemplares similares

Ejemplares similares