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Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

Heme oxygenase–1 (HO-1) is a key cytoprotective, antioxidant, and antiinflammatory molecule. The pathophysiological functions of HO-1 have been associated with its enzymatic activities in heme catabolism. We have examined the immune functions of HO-1 by its conditional ablation in myeloid cells (HO-...

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Detalles Bibliográficos
Autores principales:	Tzima, Sotiria, Victoratos, Panayiotis, Kranidioti, Ksanthi, Alexiou, Maria, Kollias, George
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715044/ https://www.ncbi.nlm.nih.gov/pubmed/19398754 http://dx.doi.org/10.1084/jem.20081582

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