Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification

Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8(+) T cell response and the evolution of th...

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Detalles Bibliográficos
Autores principales: Brumme, Zabrina L., Walker, Bruce D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715053/
https://www.ncbi.nlm.nih.gov/pubmed/19487418
http://dx.doi.org/10.1084/jem.20091094
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author Brumme, Zabrina L.
Walker, Bruce D.
author_facet Brumme, Zabrina L.
Walker, Bruce D.
author_sort Brumme, Zabrina L.
collection PubMed
description Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8(+) T cell response and the evolution of the virus during early HIV infection.
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spelling pubmed-27150532009-12-08 Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification Brumme, Zabrina L. Walker, Bruce D. J Exp Med Commentary Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8(+) T cell response and the evolution of the virus during early HIV infection. The Rockefeller University Press 2009-06-08 /pmc/articles/PMC2715053/ /pubmed/19487418 http://dx.doi.org/10.1084/jem.20091094 Text en © 2009 Brumme and Walker This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Brumme, Zabrina L.
Walker, Bruce D.
Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
title Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
title_full Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
title_fullStr Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
title_full_unstemmed Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
title_short Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification
title_sort tracking the culprit: hiv-1 evolution and immune selection revealed by single-genome amplification
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715053/
https://www.ncbi.nlm.nih.gov/pubmed/19487418
http://dx.doi.org/10.1084/jem.20091094
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