Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

Identification of full-length transmitted HIV-1 genomes could be instrumental in HIV-1 pathogenesis, microbicide, and vaccine research by enabling the direct analysis of those viruses actually responsible for productive clinical infection. We show in 12 acutely infected subjects (9 clade B and 3 cla...

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Detalles Bibliográficos
Autores principales: Salazar-Gonzalez, Jesus F., Salazar, Maria G., Keele, Brandon F., Learn, Gerald H., Giorgi, Elena E., Li, Hui, Decker, Julie M., Wang, Shuyi, Baalwa, Joshua, Kraus, Matthias H., Parrish, Nicholas F., Shaw, Katharina S., Guffey, M. Brad, Bar, Katharine J., Davis, Katie L., Ochsenbauer-Jambor, Christina, Kappes, John C., Saag, Michael S., Cohen, Myron S., Mulenga, Joseph, Derdeyn, Cynthia A., Allen, Susan, Hunter, Eric, Markowitz, Martin, Hraber, Peter, Perelson, Alan S., Bhattacharya, Tanmoy, Haynes, Barton F., Korber, Bette T., Hahn, Beatrice H., Shaw, George M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715054/
https://www.ncbi.nlm.nih.gov/pubmed/19487424
http://dx.doi.org/10.1084/jem.20090378

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