Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

We describe new T cell receptor (TCR) transgenic mice (relapsing-remitting [RR] mice) carrying a TCR specific for myelin oligodendrocyte glycoprotein (MOG) peptide 92–106 in the context of I-A(s). Backcrossed to the SJL/J background, most RR mice spontaneously develop RR experimental autoimmune ence...

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Detalles Bibliográficos
Autores principales: Pöllinger, Bernadette, Krishnamoorthy, Gurumoorthy, Berer, Kerstin, Lassmann, Hans, Bösl, Michael R., Dunn, Robert, Domingues, Helena S., Holz, Andreas, Kurschus, Florian C., Wekerle, Hartmut
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715069/
https://www.ncbi.nlm.nih.gov/pubmed/19487416
http://dx.doi.org/10.1084/jem.20090299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715069/
https://www.ncbi.nlm.nih.gov/pubmed/19487416
http://dx.doi.org/10.1084/jem.20090299

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