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The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
Central tolerance is shaped by the array of self-antigens expressed and presented by various types of thymic antigen-presenting cells (APCs). Depending on the overall signal quality and/or quantity delivered in these interactions, self-reactive thymocytes either apoptose or commit to the T regulator...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715082/ https://www.ncbi.nlm.nih.gov/pubmed/19564355 http://dx.doi.org/10.1084/jem.20082449 |