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The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

Central tolerance is shaped by the array of self-antigens expressed and presented by various types of thymic antigen-presenting cells (APCs). Depending on the overall signal quality and/or quantity delivered in these interactions, self-reactive thymocytes either apoptose or commit to the T regulator...

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Detalles Bibliográficos
Autores principales:	Koble, Christian, Kyewski, Bruno
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715082/ https://www.ncbi.nlm.nih.gov/pubmed/19564355 http://dx.doi.org/10.1084/jem.20082449

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